BECAS MAX PLANCK / FUNDACIÓN BUNGE Y BORN / FUNDACIÓN WILLIAMS

Concurso

2018

Study of α-Synuclein’s Post-Translational Modifications by Mass Spectrometry

Ezequiel Giménez

Max Planck Institute for Biophysical Chemistry

Although diverse α-Synuclein´s Post Translational Modifications (aSyn´s PTMs) have been identified, a precise correlation with the development of Parkinson Disease (PD) has not yet been established. We propose that different PTMs (such as oxidation and nitration) could be responsible for the molecular events that leads to aSyn´s gain of toxic function. In this context, our main aim in this project is to identify potential toxic aSyn´s PTMs employing state-of-the-arts Mass Spectrometry methods. This will allow us to establish models to study aSyn´s PTMs in complex samples as a way to understand the initial events that trigger the progression of PD.

RECIBÍ NUESTRAS NOVEDADES

SEGUINOS

  • LinkedIn - Gris Círculo
  • Facebook - Gris Círculo
  • YouTube - Gris Círculo
  • Instagram - Gris Círculo
  • RSS - Gris Círculo

Somos una organización sin fines de lucro fundada en 1963, con sede en Buenos Aires, Argentina. Promovemos el conocimiento y la innovación en beneficio de nuestra sociedad.

Tel. +54 (11) 4318-6600

25 de Mayo 501 6º Piso

Ciudad Autónoma de Buenos Aires

ARGENTINA

©2019 Fundación Bunge y Born / Política de privacidad